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Polynucleotides Treatments

Here at White Swan Aesthetics we’re thrilled to introduce an innovative addition to our range of aesthetic treatments – Polynucleotides!

We’re constantly striving to bring you the latest advancements in beauty and skincare and we believe that Polynucleotides are a game-changer in the world of rejuvenation.

What Are Polynucleotides?

In simple terms, polynucleotides are natural molecules found in our bodies that play a crucial role in cell function and growth. In skin rejuvenation and facial aesthetics, polynucleotides are used to improve the appearance and health of the skin.
Polynucleotide Therapy, or PNT, is a cutting edge treatment which uses naturally occurring substances to stimulate tissue regeneration.

Derived from DNA, polynucleotides are known for their ability to enhance cell repair and renewal, promoting a youthful and radiant appearance.
Treatments can be used anywhere on the face and body but is particularly effective to treat and significantly improve the under eye area. It’s the perfect alternative for clients who want to see improvement in this area without the use of fillers.

Here’s a straightforward breakdown of how they’re used:

Skin Rejuvenation:

Polynucleotides are injected into the skin to help stimulate collagen and elastin production. This makes the skin firmer, smoother, and more youthful-looking. Treatment can also reduce the appearance of fine lines, wrinkles, and sagging. They can also help with issues such acne scars or uneven pigmentation.

Overall, polynucleotides provide a natural way to enhance the skin’s appearance by promoting its own rejuvenation processes. They’re considered safe and effective when administered by trained professionals, offering patients a non-invasive option for achieving smoother, more youthful-looking skin.

Here at White Swan Aesthetics all our practitioners are medically qualified and experienced doctors and dentists with the special expertise required to deliver this treatment effectively.

What kind of skin conditions and applications are Polynucleotides used to treat?

Polynucleotides have been shown to be effective in treating various skin conditions, including wrinkles, fine lines, scars, and stretch marks. The regenerative properties of polynucleotides promote collagen production, improve skin elasticity, and enhance overall skin texture. Additionally, this treatment can be used to improve the appearance of the face, neck, décolletage, and hands.

When it comes to wrinkles, polynucleotides work wonders by stimulating the production of collagen, a protein that provides structure and support to the skin. As we age, the production of collagen slows down, leading to the formation of wrinkles and fine lines. By introducing polynucleotides into the skin, we can kickstart the collagen production process, resulting in smoother and more youthful-looking skin.

Scars, whether they are caused by acne, surgery, or injury, can be a source of self-consciousness for many people. Polynucleotides offer a solution by promoting the regeneration of skin cells and tissue. This helps to fade the appearance of scars over time, allowing individuals to regain their confidence and feel more comfortable in their own skin.

Stretch marks, often associated with pregnancy or rapid weight gain, can be a cause of distress for many individuals. Polynucleotides have been found to improve the appearance of stretch marks by stimulating the production of elastin, a protein responsible for maintaining skin elasticity. With regular treatment, stretch marks can become less noticeable, giving individuals a renewed sense of confidence.

Do Polynucleotide treatments use fish DNA?

Yes, polynucleotide treatments do involve the use of fish DNA. However, it’s important to note that the DNA fragments used are extracted from fish, primarily salmon, and then processed to ensure their compatibility with human skin. The DNA fragments act as a stimulant for the regeneration of skin cells, helping to improve the skin’s appearance.
When applied to the skin, the polynucleotide solution interacts with the cells, specifically fibroblasts, which are responsible for producing collagen and elastin. The fish DNA fragments act as a signal, triggering the fibroblasts to increase their production of these essential proteins. As a result, the skin becomes firmer, smoother, and more youthful-looking.

It’s worth noting that polynucleotide treatments have been extensively researched and tested to ensure their safety and efficacy. With over ninety clinical trials and a proven track record in tissue and cartilage regenerative medicine, the evidence for Polynucleotides efficacy is undisputed in both aesthetic and medical fields. The use of this type of DNA in these treatments is carefully regulated to meet the highest standards of quality and purity.

How is Polynucleotide treatment performed?

Polynucleotide treatment typically involves a series of injections into the targeted area. The procedure is minimally invasive and is performed in one of our clinics. Prior to the treatment, a topical anaesthetic may be applied to minimise any discomfort. The injections are strategically placed to deliver the polynucleotides directly into the deeper layers of the skin.
Once the local anaesthetic has taken effect, the healthcare professional will begin the polynucleotide treatment. They will carefully cleanse the targeted area to ensure it is free from any impurities that could potentially interfere with the treatment’s effectiveness. This step is crucial in preparing the skin for the injections and maximising the absorption of the polynucleotides.

Next, using a fine needle, the doctor will administer the polynucleotide solution into the skin. The injections are strategically placed to target specific areas of concern, such as wrinkles, fine lines, or areas with reduced elasticity. The doctor has a thorough understanding of facial anatomy and will carefully select the injection sites to achieve the desired results.

During the procedure, patients may experience a mild stinging or discomfort as the injections are being administered. However, the anaesthetic applied beforehand helps to minimise any potential pain. The entire process is relatively quick, with most treatments taking around 30 minutes to complete.

After the treatment, patients may experience some redness, swelling, or bruising at the injection sites. These side effects are typically mild and subside within a few days.

It is important to follow the post-treatment instructions to ensure optimal results and minimise any potential complications.

Over time, as the polynucleotides stimulate collagen production and improve skin elasticity, patients may notice a gradual improvement in the appearance of their skin. Three or four sessions may be needed to achieve the desired outcome, and your doctor will work closely with you to develop a personalised treatment plan.

In conclusion, polynucleotide treatment is a minimally invasive procedure that involves strategically injecting a solution into the deeper layers of the skin. By targeting specific areas of concern, this treatment aims to improve skin elasticity, reduce wrinkles, and enhance overall skin appearance. With proper care and adherence to the treatment plan, patients can enjoy long-lasting results and a rejuvenated complexion.

How quickly will I see results?

The timeframe for seeing results from polynucleotide treatment may vary from person to person. Some individuals may start noticing improvements in their skin’s texture and appearance soon after the initial treatment. However, it’s important to understand that optimal results are usually achieved over a series of three to four treatments, typically spaced three weeks apart.

How long do treatment results last?

The duration of the treatment results can vary depending on individual factors such as age, overall skin condition, and lifestyle habits. Generally, the effects of polynucleotide treatment can last for several months to a year. However, periodic maintenance treatments may be recommended to sustain and further enhance the results.

How often should I have treatments?

The recommended frequency of polynucleotide treatments can vary depending on individual needs and desired outcomes. Initially, a series of treatments may be scheduled at intervals of three to four weeks. After achieving the desired results, maintenance treatments can typically be scheduled every three to six months to prolong the effects.

Are there any side effects?

Polynucleotide treatments are generally well-tolerated with minimal side effects. Some individuals may experience temporary redness, swelling, or mild discomfort at the injection sites, which typically resolves within a few hours to a few days. Serious complications are very rare but can include infection or allergic reactions. It’s always important to consult with one of our qualified doctors to assess your suitability for the treatment and discuss any potential risks.

Is there a recommended aftercare process?

After receiving polynucleotide treatment, it’s essential to follow the recommended aftercare instructions provided by the doctor. This may include avoiding excessive sun exposure, using gentle skincare products, and adhering to any specific post-treatment recommendations. It’s important to give your skin time to heal and avoid any activities that could potentially compromise the results of the treatment.

What is the difference between Profhilo treatment and Polynucleotide treatment?

Basically, Profhilo primarily focuses on hydrating and improving skin laxity using hyaluronic acid, whereas polynucleotide treatments aim to regenerate and rejuvenate the skin by stimulating cellular activity using polynucleotides derived from DNA or RNA.

Is it beneficial to have Profhilo and Polynucleotide treatments simultaneously?

In certain treatment situations it is possible to combine the treatments and have both at the same time. As always, the medical practitioner at White Swan Aesthetics will advise you as to the most suitable treatments to best suit your individual circumstances.

In conclusion, polynucleotides are proving to be a valuable tool in the world of skin regeneration. With their regenerative properties and broad range of applications, they hold great promise in addressing various skin concerns and rejuvenating the appearance of the skin. For more information or to book a complimentary appointment call please get in touch today.

White Swan has been awarded the “Top Doctor” badge by the global platform Realself where we showcase examples of our doctors work, have a 5 star review rating and offer expert advice to clients and other practitioners. Our clinics also feature on the UK based Consulting Room platform which highlights the best aesthetic clinics in the country.

Free 15 Minute Consultation

At White Swan Aesthetics we offer a free 15 minute consultation on your first visit.

All of our practitioners are highly qualified and experienced doctors and dentists.

Polynucleotide under eye


More Information

purpleswanicon (1)

Procedure time

30 mins – 3/4 treatment course required

Time it takes to work

4-6 weeks

Back to work



Topical local

Sensitivity period

1 hour

Duration of results

6-12 months


Bruising, swelling, redness

Full recovery

24 hours